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The significance of m6A RNA methylation regulators in predicting the prognosis and clinical course of HBV-related hepatocellular carcinoma

17 Jun 2020

Abstract excerpt

BACKGROUND: Hepatocarcinogenesis is reportedly correlated with abnormal m6A modifications; however, it is unknown whether m6A RNA methylation regulators facilitate the occurrence of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Thus, we constructed an m6A-related model that may enhance HBV-related HCC prognosis. METHODS: Gene signatures of HNRNPA2B1 and RBM15 were generated by univariate and...

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PMID: 32552682
DOI: 10.1186/s10020-020-00185-z

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