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Genome-Wide Profiling of DNA Methylation and Tumor Progression in Human Hepatocellular Carcinoma

1 Jan 2014

Abstract excerpt

OBJECTIVE: To clarify the progression pattern of abnormal DNA methylation during the development of hepatocellular carcinoma (HCC) using a comprehensive methylation assay. METHODS: We used an Infinium HumanMethylation450 BeadChip array that can analyze >485,000 CpG sites distributed throughout the genome for a comprehensive methylation study of 117 liver tissues consisting of 59 HCC and 58 noncancerous livers....

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Share to Epigenetics and DNA Methylation
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PMID: 25376281
DOI: 10.1159/000367982

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