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Article

A novel rabies vaccine based on infectious propagating particles derived from hybrid VEEV-Rabies replicon

1 Jun 2020

Abstract excerpt

BACKGROUND: Live attenuated vaccines (LAVs) can mimic natural infection and have advantages to stimulate a robust and sustained immune response as well as to confer long-term protection. However, safety concerns is one of the major obstacles for LAVs development. In an effort to achieve the optimal balance between immunogenicity and safety, researchers currently have taken different strategies for the development...

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PMID: 32512518
DOI: 10.1016/j.ebiom.2020.102819

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