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Article

XmnI Polymorphism in Sickle Cell Disease in North Morocco.

Hemoglobin - 1 May 2020

Alaoui-Ismaili Fatima-Zahra, Laghmich Achraf, Ghailani-Nourouti Naima, Barakat Amina, Bennani-Mechita Mohcine

Abstract excerpt

Sickle cell disease is one of the most common severe monogenic disorders in the world. The -158 XmnI polymorphism (C>T) of the Gγ-globin gene promoter is known to be associated with increased expression of the Gγ-globin gene, thus, higher production of Hb F and lesser clinical severity. This study aims to determine the frequency of the XmnI polymorphism and its association with Hb F levels as a modulating factor...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32508152
DOI: 10.1080/03630269.2020.1772284

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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