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Article

Association with CYP2C19 polymorphisms and Clopidogrel in treatment of elderly stroke patients.

BMC neurology - 9 Mar 2021

Li Changqing, Jia Weihua, Li Jian, Li Fangfei, Ma Jing, Zhou Lichun

Abstract excerpt

BACKGROUND: Clopidogrel is an antiplatelet drug used in the treatment of ischemic stroke. Safety and efficacy of clopidogrel has been confirmed in CAPRIE, PRoFESS trials. However, these studies focused on patients aged less than 75 years. CYP2C19 polymorphisms resulted in individual differences in clopidogrel response. Our objective was to determine whether elderly stroke patients aged over 75 years would benefit...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C19

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 33685396
DOI: 10.1186/s12883-021-02127-6
PMCID: PMC7941922

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