Article
Virulence factors regulation by the quorum-sensing and Rsm systems in the marine strain Pseudomonas aeruginosa ID4365, a natural mutant in lasR.
FEMS microbiology letters - 1 Jun 2020
Cocotl-Yañez Miguel, Soto-Aceves Martín Paolo, González-Valdez Abigail, Servín-González Luis, Soberón-Chávez Gloria
Abstract excerpt
Pseudomonas aeruginosa is an opportunistic human pathogen that is able to produce several virulence factors such as pyocyanin, rhamnolipids and elastase. In the clinical reference strain PAO1, synthesis of these virulence factors is regulated transcriptionally by quorum sensing (QS) and post-transcriptionally by the Rsm system. Herein, we investigated the role of these systems in the control of the pyocyanin,...
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