Article
NPM1 Biology in Myeloid Neoplasia.
Current hematologic malignancy reports - 1 Aug 2020
Patel Sanjay S, Kluk Michael J, Weinberg Olga K
Abstract excerpt
PURPOSE OF REVIEW: Nucleophosmin (NPM1) mutations are encountered in myeloid neoplasia and are present in ~ 30% of de novo acute myeloid leukemia cases. This review summarizes features of mutant NPM1-related disease, with a particular emphasis on recent discoveries relevant to disease monitoring, prognostication, and therapeutic intervention. RECENT FINDINGS: Recent studies have shown that HOX/MEIS gene...
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