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Targeted repression of Plasmodium apicortin by host microRNA impairs malaria parasite growth and invasion

1 Jun 2020

Abstract excerpt

ABSTRACT Mature human erythrocytes contain a rich pool of microRNAs (miRNAs), which result from differentiation of the erythrocytes during the course of haematopoiesis. Recent studies have described the effect of erythrocytic miRNAs on the invasion and growth of the malaria parasite Plasmodium falciparum during the asexual blood stage of its life cycle. In this work, we have identified two erythrocytic miRNAs,...

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PMID: 32493727
DOI: 10.1242/dmm.042820

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