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Article

Rapid generation of rotavirus single-gene reassortants by means of eleven plasmid-only based reverse genetics.

The Journal of general virology - 1 Aug 2020

Fukuda Saori, Hatazawa Riona, Kawamura Yoshiki, Yoshikawa Tetsushi, Murata Takayuki, Taniguchi Koki, Komoto Satoshi

Abstract excerpt

Reassortment is an important mechanism in the evolution of group A rotaviruses (RVAs), yielding viruses with novel genetic and phenotypic traits. The classical methods for generating RVA reassortants with the desired genetic combinations are laborious and time-consuming because of the screening and selection processes required to isolate a desired reassortant. Taking advantage of a recently developed RVA reverse...

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Source

Identifiers

PMID: 32490794
DOI: 10.1099/jgv.0.001443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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