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Article

Multiple mutations at exon 2 of RHOA detected in plasma from patients with peripheral T-cell lymphoma.

Blood advances - 9 Jun 2020

Ottolini Barbara, Nawaz Nadia, Trethewey Christopher S, Mamand Sami, Allchin Rebecca L, Dillon Richard, Fields Paul A, Ahearne Matthew J, Wagner Simon D

Abstract excerpt

The mutational landscape of peripheral T-cell lymphoma (PTCL) is being revealed through sequencing of lymph node samples, but there has been little work on the mutational load that is present in cell-free DNA (cfDNA) from plasma. We report targeted sequencing of cfDNA from PTCL patients to demonstrate c.50G>T (p.Gly17Val) in RHOA as previously described in angioimmunoblastic T-cell lymphoma (AITL) and a group of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32484856
DOI: 10.1182/bloodadvances.2019001075
PMCID: PMC7284097

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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