Article
G-quadruplexes in H1N1 influenza genomes.
BMC genomics - 23 Jan 2021
Brázda Václav, Porubiaková Otília, Cantara Alessio, Bohálová Natália, Coufal Jan, Bartas Martin, Fojta Miroslav, Mergny Jean-Louis
Abstract excerpt
BACKGROUND: Influenza viruses are dangerous pathogens. Seventy-Seven genomes of recently emerged genotype 4 reassortant Eurasian avian-like H1N1 virus (G4-EA-H1N1) are currently available. We investigated the presence and variation of potential G-quadruplex forming sequences (PQS), which can serve as targets for antiviral treatment. RESULTS: PQS were identified in all 77 genomes. The total number of PQS in...
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