Article
Anti-COVID-19 Activity of FDA Approved Drugs through RNA G-quadruplex Binding
2022-06-01
Abstract excerpt
The COVID-19 pandemic caused by SARS-CoV-2 has caused millions of infections and deaths worldwide. Limited treatment options and the threat from emerging variants underline the need for novel and widely accessible therapeutics. G-quadruplexes (G4s) are nucleic acid secondary structures known to affect many cellular processes including viral replication and transcription. We identified heretofore not reported G4s w...
Topics
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- Advanced biosensing and bioanalysis techniques
- Animal Virus Infections Studies
- Bacteriophages and microbial interactions
- DNA and Nucleic Acid Chemistry
- RNA and protein synthesis mechanisms
- SARS-CoV-2 and COVID-19 Research
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
Identifiers and source
- Literature Corpus work
- a3294415-5f80-5abd-954a-091a0a138ec4
- DOI
- 10.1101/2022.05.31.493843