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Article

Ionizing Radiation Alters the Transition/Transversion Ratio in the Exome of Human Gingiva Fibroblasts.

Health physics - 1 Jul 2020

Nath Neetika, Hagenau Lisa, Weiss Stefan, Tzvetkova Ana, Jensen Lars R, Kaderali Lars, Port Matthias, Scherthan Harry, Kuss Andreas W

Abstract excerpt

Little is known about the mutational impact of ionizing radiation (IR) exposure on a genome-wide level in mammalian tissues. Recent advancements in sequencing technology have provided powerful tools to perform exome-wide analyses of genetic variation. This also opened up new avenues for studying and characterizing global genomic IR-induced effects. However, genotypes generated by next generation sequencing (NGS)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32483046
DOI: 10.1097/HP.0000000000001251

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