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Article

Thermoneutral conditions correct the obese phenotype in female, but not male, Kiss1r knockout mice.

Journal of thermal biology - 1 May 2020

Halvorson C L, De Bond J P, Maloney S K, Smith J T

Abstract excerpt

Kisspeptin, a neuropeptide that activates gonadotropin-releasing hormone (GnRH) neurons, has also been implicated as a regulator of energy balance. Kisspeptin receptor (Kiss1r) knockout (KO) mice display an obese phenotype in adulthood compared to wild-type (WT) controls due to reduced energy expenditure. Additionally, experimental evidence shows that the temperature of typical rodent housing conditions (22 °C)...

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Source

Identifiers

PMID: 32479387
DOI: 10.1016/j.jtherbio.2020.102592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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