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Article

Obesity-induced hypogonadism in the male: premature reproductive neuroendocrine senescence and contribution of Kiss1-mediated mechanisms.

Endocrinology - 1 Mar 2014

Sánchez-Garrido Miguel Angel, Ruiz-Pino Francisco, Manfredi-Lozano Maria, Leon Silvia, Garcia-Galiano David, Castaño Justo P, Luque Raul M, Romero-Ruiz Antonio, Castellano Juan M, Diéguez Carlos, Pinilla Leonor, Tena-Sempere Manuel

Abstract excerpt

Reproduction is sensitive to insufficient body energy reserves, especially in females. Metabolic regulation of the male reproductive axis is less obvious, and the impact of conditions of persistent energy excess has received moderate attention. Yet, the escalating prevalence of obesity and the clinical evidence of its deleterious effects on male fertility have raised considerable concerns. We report here...

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Source

Identifiers

PMID: 24424048
DOI: 10.1210/en.2013-1584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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