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HSPA1A gene polymorphism rs1008438 is associated with susceptibility to acute mountain sickness in Han Chinese individuals.

Molecular genetics & genomic medicine - 1 Aug 2020

Liu Zhicheng, Chen Hong, Xu Ting, Wang Xiaomei, Yao Chunyan

Abstract excerpt

BACKGROUND: Acute mountain sickness (AMS) usually occurs among non-acclimated individuals after rapid ascending to high-altitude environments (generally ≥2,500 m). However, the precise molecular mechanism of AMS remains unclear. Our study aimed to investigate the relationship between several single nucleotide polymorphisms (SNPs) and AMS susceptibility. METHODS: In this work, sequencing data were obtained from 69...

Topics

Adult
Altitude Sickness
China
HSP70 Heat-Shock Proteins
Humans
Male
Polymorphism, Single Nucleotide

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32478477
DOI: 10.1002/mgg3.1322
PMCID: PMC7434611

Genes

HSPA1A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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