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Article

Polymorphisms of hypoxia-related genes in subjects susceptible to acute mountain sickness.

Respiration; international review of thoracic diseases - 1 Jan 2011

Ding Hui, Liu Qiuling, Hua Minglei, Ding Mengjiang, Du Haike, Zhang Weilong, Li Zengde, Zhang Jianpeng

Abstract excerpt

BACKGROUND: The occurrence of acute mountain sickness (AMS), which develops in some individuals who ascend to altitudes above 2,500 m, may be associated with 4 hypoxia-related genes (HIF-1, VEGFA, HSP-70 and eNOS). OBJECTIVES: The aim of our study was to investigate the potential role of the 4 hypoxia-related genes in AMS pathogenesis. We therefore evaluated single-nucleotide polymorphisms (SNPs) of the genes in...

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Altitude Sickness
Asian People
HSP70 Heat-Shock Proteins
Hypoxia
Hypoxia-Inducible Factor 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Military Personnel

Nitric Oxide Synthase Type III

Vascular Endothelial Growth Factor A

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Identifiers

PMID: 21242666
DOI: 10.1159/000322850

Genes

VEGFA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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