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Article

The genetics of altitude tolerance: the evidence for inherited susceptibility to acute mountain sickness.

Journal of occupational and environmental medicine - 1 Feb 2011

MacInnis Martin J, Wang Pei, Koehle Michael S, Rupert Jim L

Abstract excerpt

OBJECTIVE: Acute mountain sickness (AMS) has become a significant environmental health issue as improvements in transportation, "environmental tourism," and resource development lure more people to the highlands. Whether there is a genetic contribution to AMS susceptibility is a central question in high-altitude medicine. This article provides a systematic review of the evidence supporting such an innate...

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Identifiers

PMID: 21270658
DOI: 10.1097/JOM.0b013e318206b112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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