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Article

EPAS1 and EGLN1 associations with high altitude sickness in Han and Tibetan Chinese at the Qinghai-Tibetan Plateau.

Blood cells, molecules & diseases - 15 Aug 2012

Buroker Norman E, Ning Xue-Han, Zhou Zhao-Nian, Li Kui, Cen Wei-Jun, Wu Xiu-Feng, Zhu Wei-Zhong, Scott C Ronald, Chen Shi-Han

Abstract excerpt

High altitude sickness (HAS) occurs among humans visiting or inhabiting high altitude environments. Genetic differences in the EPAS1 and EGLN1 genes have been found between lowland (Han) and highland (Tibetan) Chinese. Three SNPs within EPAS1 and EGLN1 were evaluated in Han and Tibetan patients with acute mountain sickness (AMS) and chronic mountain sickness (CMS). We compared 85 patients with AMS to 79 Han...

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Source

Identifiers

PMID: 22595196
DOI: 10.1016/j.bcmd.2012.04.004

Genes

EGLN1
EPAS1

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