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Article

Targeting bedaquiline mycobacterial efflux pump to potentially enhance therapy in Mycobacterium abscessus.

International journal of mycobacteriology - 1 Jan 2000

Martin Anandi, Bouyakoub Yasmine, Soumillion Kate, Mantu El Onore Ngyuvula, Colmant Alexandre, Rodriguez-Villalobos Hector

Abstract excerpt

Background: Mycobacterium abscessus is notorious for being intrinsically resistant to most antibiotics. Antibiotic efflux is one of the mechanisms used by M. abscessus to pump out antibiotics from their cells. Inhibiting efflux pumps (EPs) can be an attractive strategy to enhance the activity of drugs. The objective of this study is to determine the activity of EP inhibitors (EPIs) to enhance the efficacy of the...

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Identifiers

PMID: 32474492
DOI: 10.4103/ijmy.ijmy_181_19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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