Article
In Vitro Activity of Bedaquiline against Nontuberculous Mycobacteria in China.
Antimicrobial agents and chemotherapy - 1 May 2017
Pang Yu, Zheng Huiwen, Tan Yaoju, Song Yuanyuan, Zhao Yanlin
Abstract excerpt
The main goal of our study was to evaluate the in vitro bedaquiline susceptibility of six prevalent species of pathogenic nontuberculous mycobacteria (NTM) in China. In addition, we investigated the potential molecular mechanisms contributing to bedaquiline resistance in the different NTM species. Among slowly growing mycobacteria (SGM), bedaquiline exhibited the highest activity against Mycobacterium avium; the...
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