Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bedaquiline Inhibits the ATP Synthase in Mycobacterium abscessus and Is Effective in Infected Zebrafish.

Antimicrobial agents and chemotherapy - 1 Nov 2017

Dupont Christian, Viljoen Albertus, Thomas Sangeeta, Roquet-Banères Françoise, Herrmann Jean-Louis, Pethe Kevin, Kremer Laurent

Abstract excerpt

Pulmonary infections caused by Mycobacterium abscessus are emerging as a global threat, especially in cystic fibrosis patients. Further intensifying the concern of M. abscessus infection is the recent evidence of human-to-human transmission of the infection. M. abscessus is a naturally multidrug-resistant fast-growing pathogen for which pharmacological options are limited. Repurposing antitubercular drugs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphate
Share to Antitubercular Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diarylquinolines

Share to Drug Resistance, Bacterial

Share to Microbial Sensitivity Tests

Share to Mycobacterium Infections, Nontuberculous

Share to Polymorphism, Single Nucleotide

Share to Zebrafish

Source

Open in PubMed Open full text

Identifiers

PMID: 28807917
DOI: 10.1128/AAC.01225-17
PMCID: PMC5655087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bedaquiline Inhibits the ATP Synthase in Mycobacterium abscessus and Is Effective in Infected Zebrafish.PMID 28807917Read ↗

Pathogen Box screening for hit identification against Mycobacterium abscessusSemantic proximity Read ↗

Determination of MIC Distribution and Mechanisms of Decreased Susceptibility to Bedaquiline among Clinical Isolates of Mycobacterium abscessusSemantic proximity Read ↗

The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infectionSemantic proximity Read ↗

Pharmacological validation of dihydrofolate reductase as a drug target in Mycobacterium abscessusSemantic proximity Read ↗

The novel drug candidate VOMG kills Mycobacterium abscessus and other pathogens by inhibiting cell divisionSemantic proximity Read ↗

A Mycobacterium tuberculosis cytochrome bd oxidase mutant is hypersensitive to bedaquiline.Semantic proximity Read ↗

Pipeline of anti‐Mycobacterium abscessussmall molecules: Repurposable drugs and promising novel chemical entitiesSemantic proximity Read ↗

Rifabutin Is Active against Mycobacterium abscessus ComplexSemantic proximity Read ↗

Mycothione reductase as a potential target in the fight against Mycobacterium abscessus infectionsSemantic proximity Read ↗

The Diverse Cellular and Animal Models to Decipher the Physiopathological Traits of Mycobacterium abscessus InfectionSemantic proximity Read ↗

Targeting bedaquiline mycobacterial efflux pump to potentially enhance therapy in Mycobacterium abscessus.Semantic proximity Read ↗

A new piperidinol derivative targeting mycolic acid transport in <i>Mycobacterium abscessus</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.