Article
Single amino acid change at position 255 in rabies virus glycoprotein decreases viral pathogenicity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2020
Luo Jun, Zhang Boyue, Lyu Ziyu, Wu Yuting, Zhang Yue, Guo Xiaofeng
Abstract excerpt
Previous studies have indicated that the amino acid at position 333 in the glycoprotein (G) is closely related to rabies virus (RABV) pathogenicity. However, whether there are other amino acid residues in G that relate to pathogenicity remain unclear. The aim of this study is to find new amino acid residues in G that could strongly reduce RABV pathogenicity. The present study found that the pathogenicity of a...
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