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Article

Multiple amino acids in the glycoprotein of rabies virus are responsible for pathogenicity in adult mice.

Virus research - 1 Feb 2006

Takayama-Ito Mutsuyo, Ito Naoto, Yamada Kentaro, Sugiyama Makoto, Minamoto Nobuyuki

Abstract excerpt

We have reported that the region between amino acids 164 and 303 in the glycoprotein of rabies Nishigahara strain is important for lethality in adult mice. The region contains nine amino acid substitutions between the virulent Nishigahara and the avirulent RC-HL strains. In order to determine key residues for the pathogenicity, two chimeric strains and seven mutants were generated and examined for...

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Source

Identifiers

PMID: 16188341
DOI: 10.1016/j.virusres.2005.08.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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