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Article

Association of HLA-DRB1*04:05 allele with drug-induced interstitial lung disease in Japanese population.

The pharmacogenomics journal - 1 Dec 2020

Imatoh Takuya, Ushiki Atsuhito, Ota Masao, Ito Michiko, Sekine Akihiro, Yamashita Taiki, Mashimo Yoichi, Nakamura Ryosuke, Saito Kosuke, Saito Yoshiro, Hanaoka Masayuki

Abstract excerpt

Drug-induced interstitial lung disease (DILD) is a life-threatening adverse reaction. The Japanese population is more susceptible to DILD as compared with other populations, suggesting its pathogenesis could vary depending on ethnic genetic background. We conducted case-control studies to elucidate the association between DILD and HLA alleles in the Japanese. The 177 clinically diagnosed DILD patients and 3002...

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PMID: 32467566
DOI: 10.1038/s41397-020-0172-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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