Article
Association of polymorphisms in metastasis suppressor genes NME1 and KISS1 with breast cancer development and metastasis.
Journal of the Egyptian National Cancer Institute - 27 May 2020
Antar Sarah, Mokhtar Naglaa, Abd Elghaffar Mahmoud Adel, Seleem Amal K
Abstract excerpt
BACKGROUND: NME1 and KISS1 genes are two tumor metastasis suppressor genes, mapped to chromosomes 17q21.3 and 1q32 respectively. Here, we analyzed the association of EcoR1 (rs34214448-G/T) polymorphism in NME1 gene and 9 del T (rs5780218-A/-) polymorphism in KISS1 gene with breast cancer development and metastasis. RESULTS: The study included 75 women newly diagnosed with breast cancer recruited from Oncology...
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