Article
Polymorphisms rs12998 and rs5780218 in KiSS1 suppressor metastasis gene in Mexican patients with breast cancer.
Disease markers - 1 Jan 2015
Quevedo Edhit Guadalupe Cruz, Aguilar Gabriela Monserrat Mimendi, Aguilar Luis Anselmo Juárez, Rubio Susan Andrea Gutierrez, Martínez Silvia Esperanza Flores, Rodríguez Ingrid Patricia Dávalos, Corona José Sánchez, Morán Martha Isabel Torres, Gómez Roberto Carlos Rosales, Moguel María Cristina Morán
Abstract excerpt
AIMS: KiSS1 is a metastasis suppressor gene associated with inhibition of cellular chemotaxis and invasion attenuating the metastasis in melanoma and breast cancer cell lines. Along the KiSS-1 gene at least 294 SNPs have been described; however the association of these polymorphisms as genetic ma...
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