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Article

The Predictive Role of PIK3CA Mutation Status on PI3K Inhibitors in HR+ Breast Cancer Therapy: A Systematic Review and Meta-Analysis.

BioMed research international - 1 Jan 2020

Wang Mingming, Li Jin, Huang Jiangsheng, Luo Mei

Abstract excerpt

AIM: To evaluate the impact of PIK3CA mutation status on clinical outcomes of HR+ breast cancer treated with PI3K inhibitors. METHODS: A comprehensive literature search was conducted in online databases from inception to December 31, 2019. The main characteristics and prognostic data of each eligible study were extracted. The odds ratio (OR) for the overall response rate (ORR) and hazard ratio (HR) for...

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Identifiers

PMID: 32461963
DOI: 10.1155/2020/1598037
PMCID: PMC7238354

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