Article
Emergence of azole resistant-Aspergillus fumigatus infections during STAT3-deficiency.
Journal of medical microbiology - 1 Jun 2020
Danion François, Duréault Amélie, Gautier Cécile, Senechal Agathe, Persat Florence, Bougnoux Marie-Elisabeth, Givel Claire, Couderc Louis-Jean, Lortholary Olivier, Garcia-Hermoso Dea, Lanternier Fanny
Abstract excerpt
Introduction. Signal transducer and activator of transcription 3 (STAT3) deficiency is a rare primary immunodeficiency associated with increased susceptibility to bacterial and fungal infections, notably pulmonary aspergillosis.Aim. We describe the emergence of azole-resistant Aspergillus fumigatus infections in STAT3-deficient patients.Methodology. During a retrospective study of 13 pulmonary aspergillosis cases...
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