Article
Emergence of azole-resistant invasive aspergillosis in HSCT recipients in Germany.
The Journal of antimicrobial chemotherapy - 1 May 2015
Steinmann J, Hamprecht A, Vehreschild M J G T, Cornely O A, Buchheidt D, Spiess B, Koldehoff M, Buer J, Meis J F, Rath P-M
Abstract excerpt
OBJECTIVES: Aspergillus fumigatus is the most common agent of invasive aspergillosis (IA). In recent years, resistance to triazoles, the mainstay of IA therapy, has emerged in different countries worldwide. IA caused by azole-resistant A. fumigatus (ARAF) shows an exceedingly high mortality. In this study, IA due to ARAF isolates in HSCT recipients in Germany was investigated. METHODS: The epidemiology of azole...
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