Article
Genetic variation in toll like receptors 2, 7, 9 and interleukin-6 is associated with cytomegalovirus infection in late pregnancy.
BMC medical genetics - 25 May 2020
Mhandire Doreen Z, Mhandire Kudakwashe, Magadze Mulalo, Wonkam Ambroise, Kengne Andre P, Dandara Collet
Abstract excerpt
BACKGROUND: Maternal cytomegalovirus (CMV) infection and/or reactivation in pregnancy is associated with a myriad of adverse infant outcomes. However, the role of host genetic polymorphisms in modulating maternal CMV status is inconclusive. This study investigated the possible association of single nucleotide polymorphisms in toll-like receptor (TLR) and cytokine genes with maternal plasma CMV DNA status in black...
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