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Microsatellite instability and mismatch repair protein expressions in lymphocyte‐predominant breast cancer

25 May 2020

Abstract excerpt

The frequency of microsatellite instability (MSI) is reportedly extremely low in breast cancer, despite widespread clinical expectations that many patients would be responsive to immune-checkpoint inhibitors (ICI). Considering that some triple-negative breast cancers (TNBC) responded well to ICI in a clinical trial and that a high density of tumor-infiltrating lymphocytes (TILs) is frequently observed in other...

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PMID: 32449246
DOI: 10.1111/cas.14500

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