Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insufficient GDF15 expression predisposes women to unexplained recurrent pregnancy loss by impairing extravillous trophoblast invasion

4 Jun 2023

Abstract excerpt

Insufficient extravillous trophoblast (EVT) invasion during early placentation has been shown to contribute to recurrent pregnancy loss (RPL). However, the regulatory factors involved and their involvement in RPL pathogenesis remain unknown. Here, we found aberrantly decreased growth differentiation factor 15 (GDF15) levels in both first-trimester villous and serum samples of unexplained recurrent pregnancy loss...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to GDF15 and Related Biomarkers
Share to Pregnancy and preeclampsia studies
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37272232
DOI: 10.1111/cpr.13514

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insufficient GDF15 expression predisposes women to unexplained recurrent pregnancy loss by impairing extravillous trophoblast invasionPMID 37272232Read ↗

GDF15 deficiency hinders human trophoblast invasion to mediate pregnancy loss through downregulating Smad1/5 phosphorylationSemantic proximity Read ↗

Preeclampsia is Associated With Reduced ISG15 Levels Impairing Extravillous Trophoblast InvasionSemantic proximity Read ↗

Concise Review: Growth Differentiation Factor 15 in Pathology: A Clinical Role?Semantic proximity Read ↗

GDF15 and Growth ControlSemantic proximity Read ↗

EHD1 impairs decidualization by regulating the Wnt4/β-catenin signaling pathway in recurrent implantation failureSemantic proximity Read ↗

Evidence GDF15 Plays a Role in Familial and Recurrent Hyperemesis GravidarumSemantic proximity Read ↗

Fetally-encoded GDF15 and maternal GDF15 sensitivity are major determinants of nausea and vomiting in human pregnancySemantic proximity Read ↗

The enhancer RNA lnc-SLC4A1-1 epigenetically regulates unexplained recurrent pregnancy loss (URPL) by activating CXCL8 and NF-kB pathwaySemantic proximity Read ↗

Multi-ancestry genome-wide association study of severe pregnancy nausea and vomiting.Semantic proximity Read ↗

GDF8 Promotes the Cell Invasiveness in Human Trophoblasts by Upregulating the Expression of Follistatin-Like 3 Through the ALK5-SMAD2/3 Signaling PathwaySemantic proximity Read ↗

Elevated histone demethylase KDM5C increases recurrent miscarriage risk by preventing trophoblast proliferation and invasionSemantic proximity Read ↗

Associations of vomiting and antiemetic use in pregnancy with levels of circulating GDF15 early in the second trimester: A nested case-control studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.