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Evolutionary transcriptomics implicates HAND2 in the origins of implantation and regulation of gestation length

1 Feb 2021

Abstract excerpt

The developmental origins and evolutionary histories of cell types, tissues, and organs contribute to the ways in which their dysfunction produces disease. In mammals, the nature, development and evolution of maternal-fetal interactions likely influence diseases of pregnancy. Here we show genes that evolved expression at the maternal-fetal interface in Eutherian mammals play essential roles in the evolution of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33522483
DOI: 10.7554/elife.61257

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