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Engineering the Vasculature of Stem-Cell-Derived Liver Organoids

30 Jun 2021

Abstract excerpt

The vasculature of stem-cell-derived liver organoids can be engineered using methods that recapitulate embryonic liver development. Hepatic organoids with a vascular network offer great application prospects for drug screening, disease modeling, and therapeutics. However, the application of stem cell-derived organoids is hindered by insufficient vascularization and maturation. Here, we review different theories...

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PMID: 34208902
DOI: 10.3390/biom11070966

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