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Article

Bone marrow-derived mitochondrial DNA has limited capacity for inter-tissue transfer in vivo.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2020

Tarnopolsky Mark A, Kerkhof Jennifer, Stuart Alan, Bujak Adam, Nilsson Mats I, Hettinga Bart, May Linda, Rupar C Anthony, Sadikovic Bekim

Abstract excerpt

Studies have shown that mitochondrial DNA (mtDNA) can be exchanged between tissues; however, the mechanism(s) behind this phenomenon remain unclear. Exosomes and other extracellular vesicles (EVs) including microvesicles (MV) have been shown to contain mtDNA. EVs can be derived from a number of tissues; however, the source and relative proportion of EVs containing mtDNA remains unknown. We sampled whole blood and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32441840
DOI: 10.1096/fj.202000463R

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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