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Extracellular DNA in blood products and its potential effects on transfusion

1 Mar 2020

Abstract excerpt

Blood transfusions are sometimes necessary after a high loss of blood due to injury or surgery. Some people need regular transfusions due to medical conditions such as haemophilia or cancer. Studies have suggested that extracellular DNA including mitochondrial DNA present in the extracellular milieu of transfused blood products has biological actions that are capable of activating the innate immune systems and...

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PMID: 32150264
DOI: 10.1042/bsr20192770

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