Article
Molecular, histopathological, and genomic variants of glioblastoma.
Frontiers in bioscience (Landmark edition) - 1 Jun 2014
Karsy Michael, Huang Tiangui, Kleinman George, Karpel-Massler Georg
Abstract excerpt
Glioblastoma (GBM), the most common primary brain tumor, has a poor median prognosis despite modern surgical, chemotherapeutic, and radiation modalities, which have shown little clinical efficacy. Initially categorized by clinicopathological classification into de novo primary GBM and secondary GBM, which arises from lower-grade glioma, genomic studies have elucidated several distinct genotypes. In addition,...
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