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Nanopore 16S amplicon sequencing enables rapid detection of pathogen in knee periprosthetic joint infection

18 Oct 2022

Abstract excerpt

OBJECTIVES: We investigated whether nanopore 16S amplicon sequencing is capable of bacterial identification in patients with knee prosthetic joint infection (PJI), and we compared its efficacy with conventional culture studies. METHODS: In total, 36 patients who had clinical manifestation suspected of PJI were enrolled in this study. To begin, synovial fluids were aspirated from the affected knee using aseptic...

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PMID: 36288682
DOI: 10.1016/j.ijmm.2022.151570

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