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Article

Comparison of broad-range polymerase chain reaction and metagenomic next-generation sequencing for the diagnosis of prosthetic joint infection

3 Apr 2020

Abstract excerpt

PURPOSE: The aims of our study were to (1) evaluate the concordance of both methods for detecting prosthetic joint infection (PJI) pathogens in joint fluid and to (2) clarify whether broad-range polymerase chain reaction (BR-PCR) can be used as a verification method for metagenomic next-generation sequencing (mNGS) for PJI diagnosis. METHODS: In total, 63 patients underwent total joint arthroplasty, with 45 PJI...

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PMID: 32251799
DOI: 10.1016/j.ijid.2020.03.055

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