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Article

The STAT4 and not the IFNL3 variant is associated with hepatitis B virus clearance in a population from the Khyber Pakhtunkhwa region of Pakistan.

Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology - 1 Jun 2020

Jalil Ismail, Arshad Muhammad, Khan Shahtaj, Dasti Javid I

Abstract excerpt

BACKGROUND AND STUDY AIMS: Host genetic modifiers of the risk and persistence of hepatitis B virus (HBV) infection in the Pakistani population have not been clearly elucidated. Recently, two genome-wide association studies described that STAT4 and IFNL3 variants are associated with different aspects of the course of HBV infection. However, the roles of these variants in the persistence of HBV infection have not...

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PMID: 32439233
DOI: 10.1016/j.ajg.2020.04.011

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