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Article

Pseudouridine-mediated stop codon readthrough in S. cerevisiae is sequence context-independent.

RNA (New York, N.Y.) - 1 Sept 2020

Adachi Hironori, Yu Yi-Tao

Abstract excerpt

We have previously shown that when the uridine of a stop codon (UAA, UAG, or UGA) is pseudouridylated, the ribosome reads through the modified stop codon. However, it is not clear as to whether or not the pseudouridine (Ψ)-mediated readthrough is dependent on the sequence context of mRNA. Here, we use several different approaches and the yeast system to address this question. We show that when a stop codon...

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Identifiers

PMID: 32434780
DOI: 10.1261/rna.076042.120
PMCID: PMC7430670

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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