Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

THBS4 silencing regulates the cancer stem cell‐like properties in prostate cancer via blocking the PI3K/Akt pathway

18 May 2020

Abstract excerpt

BACKGROUND: Although thrombospondins 4 (THBS4) participates in controlling the biology of prostate cancer (PCa), the mechanism underlying this regulation remains unknown. Hence, this study aims to identify the regulatory effects of THBS4 on the PCa stem cell-like properties and the potential mechanism associated with the phosphatidylinositol 3'-kinase (PI3K)/protein kinase B (Akt) pathway. METHODS: PCa stem cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Cancer Cells and Metastasis
Share to Hippo pathway signaling and YAP/TAZ

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32421868
DOI: 10.1002/pros.23989

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

THBS4 silencing regulates the cancer stem cell‐like properties in prostate cancer via blocking the PI3K/Akt pathwayPMID 32421868Read ↗

The Molecular Biology of Prostate Cancer Stem Cells: From the Past to the FutureSemantic proximity Read ↗

Cancer Stem Cells in Prostate Cancer: Implications for Targeted Therapy.Semantic proximity Read ↗

BTF3 sustains cancer stem-like phenotype of prostate cancer via stabilization of BMI1Semantic proximity Read ↗

Prostate cancer stem/progenitor cells: Identification, characterization, and implicationsSemantic proximity Read ↗

Knockdown of ZEB1 reverses cancer stem cell properties in prostate cancer cellsSemantic proximity Read ↗

Phosphodiesterase 5/protein kinase G signal governs stemness of prostate cancer stem cells through Hippo pathway.Semantic proximity Read ↗

Cell division cycle 20 (CDC20) drives prostate cancer progression via stabilization of β-catenin in cancer stem-like cellsSemantic proximity Read ↗

Development of human prostate cancer stem cells involves epigenomic alteration and PI3K/AKT pathway activationSemantic proximity Read ↗

Stem cells: The root of prostate cancer?Semantic proximity Read ↗

Inhibition of STAT3 signaling targets both tumor-initiating and differentiated cell populations in prostate cancerSemantic proximity Read ↗

Prostate Cancer Stem Cells: Viewing Signaling Cascades at a Finer Resolution.Semantic proximity Read ↗

Circadian Rhythm Gene PER3 Negatively Regulates Stemness of Prostate Cancer Stem Cells via WNT/β-Catenin Signaling in Tumor MicroenvironmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.