Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Circadian Rhythm Gene PER3 Negatively Regulates Stemness of Prostate Cancer Stem Cells via WNT/β-Catenin Signaling in Tumor Microenvironment

18 Mar 2021

Abstract excerpt

Prostate cancer (PCa) cells are heterogeneous, containing a variety of cancer cells with phenotypical and functional discrepancies in the tumor microenvironment, where prostate cancer stem cells (PCSCs) play a vital role in PCa development. Our earlier studies have shown that ALDHhiCD44+ (DP) PCa cells and the corresponding ALDHloCD44– (DN) PCa cells manifest as PCSCs and non-PCSCs, respectively, but the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Circadian rhythm and melatonin
Share to Dietary Effects on Health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33816508
DOI: 10.3389/fcell.2021.656981

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Circadian Rhythm Gene PER3 Negatively Regulates Stemness of Prostate Cancer Stem Cells via WNT/β-Catenin Signaling in Tumor MicroenvironmentPMID 33816508Read ↗

Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemnessSemantic proximity Read ↗

The Molecular Biology of Prostate Cancer Stem Cells: From the Past to the FutureSemantic proximity Read ↗

Therapeutic implications of cancer stem cells in prostate cancerSemantic proximity Read ↗

Circadian disruption in cancer and regulation of cancer stem cells by circadian clock genes: An updated reviewSemantic proximity Read ↗

Concise Review: Prostate Cancer Stem Cells: Current UnderstandingSemantic proximity Read ↗

Prostate cancer stem cell dynamics in the evolution of drug resistanceSemantic proximity Read ↗

BTF3 sustains cancer stem-like phenotype of prostate cancer via stabilization of BMI1Semantic proximity Read ↗

Lineage Plasticity and Stemness Phenotypes in Prostate Cancer: Harnessing the Power of Integrated “Omics” Approaches to Explore Measurable MetricsSemantic proximity Read ↗

Increasing Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient SurvivalSemantic proximity Read ↗

Prostate cancer stem/progenitor cells: Identification, characterization, and implicationsSemantic proximity Read ↗

Phosphodiesterase 5/protein kinase G signal governs stemness of prostate cancer stem cells through Hippo pathway.Semantic proximity Read ↗

Cell division cycle 20 (CDC20) drives prostate cancer progression via stabilization of β-catenin in cancer stem-like cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.