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Article

Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes.

BMC bioinformatics - 14 May 2020

Cao Lu, der Meer Andries D van, Verbeek Fons J, Passier Robert

Abstract excerpt

BACKGROUND: Cardiotoxicity, characterized by severe cardiac dysfunction, is a major problem in patients treated with different classes of anticancer drugs. Development of predictable human-based models and assays for drug screening are crucial for preventing potential drug-induced adverse effects. Current animal in vivo models and cell lines are not always adequate to represent human biology. Alternatively, human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32408861
DOI: 10.1186/s12859-020-3466-1
PMCID: PMC7222481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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