Article

Predicting gene expression from cell morphology in human induced pluripotent stem cells

2022-04-19

Abstract excerpt

Purification is essential before differentiating human induced pluripotent stem cells (hiPSCs) into cells that fully express particular differentiation marker genes. High-quality iPSC clones are typically purified through gene expression profiling or visual inspection of the cell morphology; however, the relationship between the two methods remains unclear. We investigated the relationship between gene expression...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d503f3d7-d1c7-5096-a38d-2ffee51a2da1
DOI: 10.1101/2022.04.19.488786

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Predicting gene expression from cell morphology in human induced pluripotent stem cellsDOI 10.1101/2022.04.19.488786Read

Joint profiling of cell morphology and gene expression during <i>in vitro</i> neurodevelopmentSemantic proximity Read

Automatic identification of subcellular phenotypes on human cell arrays.Semantic proximity Read

Image-based Cell Phenotyping Using Deep LearningSemantic proximity Read

Predicting multipotency of human adult stem cells derived from various donors through deep learningSemantic proximity Read

Image-based phenotyping of disaggregated cells using deep learning.Semantic proximity Read

Single-cell phenotyping of human induced pluripotent stem cells by high-throughput imagingSemantic proximity Read

Morphology-Based Prediction of Osteogenic Differentiation Potential of Human Mesenchymal Stem CellsSemantic proximity Read

Automated Prediction of Fibroblast Phenotypes Using Mathematical Descriptors of Cellular FeaturesSemantic proximity Read

Deep Learning for Predicting Stem Cell Efficiency for use in Beta Cell DifferentiationSemantic proximity Read

Learning unsupervised feature representations for single cell microscopy images with paired cell inpaintingSemantic proximity Read

MSCProfiler: An image processing workflow to investigate Mesenchymal Stem Cell heterogeneity using imaging flow cytometry dataSemantic proximity Read

Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes.Semantic proximity Read