Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The binding of the APT1 domains to phosphoinositides is regulated by metal ions in vitro.

Biochimica et biophysica acta. Biomembranes - 1 Sept 2020

Kolakowski Damian, Kaminska Joanna, Zoladek Teresa

Abstract excerpt

Chorein is a protein of the Vps13 family, and defects in this protein cause the rare neurodegenerative disorder chorea-acanthocytosis (ChAc). Chorein is involved in the actin cytoskeleton organization, calcium ion flux, neuronal cell excitability, exocytosis and autophagy. The function of this protein is poorly understood, and obtaining this knowledge is a key to finding a cure for ChAc. Chorein, as well as the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Autophagy-Related Proteins
Share to Ions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Magnesium

Share to Phosphatidylinositol Phosphates

Share to Protein Domains

Share to Thiolester Hydrolases

Share to Vesicular Transport Proteins

Source

Identifiers

PMID: 32407779
DOI: 10.1016/j.bbamem.2020.183349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The binding of the APT1 domains to phosphoinositides is regulated by metal ions in vitro.PMID 32407779Read ↗

Amino acid substitution equivalent to human chorea-acanthocytosis I2771R in yeast Vps13 protein affects its binding to phosphatidylinositol 3-phosphate.Semantic proximity Read ↗

Yeast and other lower eukaryotic organisms for studies of Vps13 proteins in health and disease.Semantic proximity Read ↗

Insights into VPS13 properties and function reveal a new mechanism of eukaryotic lipid transport.Semantic proximity Read ↗

The Vps13p-Cdc31p complex is directly required for TGN late endosome transport and TGN homotypic fusion.Semantic proximity Read ↗

Structural and functional studies of TBC1D23 C-terminal domain provide a link between endosomal trafficking and PCHSemantic proximity Read ↗

SEA and GATOR 10 Years Later.Semantic proximity Read ↗

The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus.Semantic proximity Read ↗

The Vps13 Family of Lipid Transporters and Its Role at Membrane Contact Sites.Semantic proximity Read ↗

Vtc5 is localized to the vacuole membrane by the conserved AP-3 complex to regulate polyphosphate synthesis in budding yeastSemantic proximity Read ↗

Chorein-sensitive polymerization of cortical actin and suicidal cell death in chorea-acanthocytosis.Semantic proximity Read ↗

Drosophila Vps13 Is Required for Protein Homeostasis in the Brain.Semantic proximity Read ↗

A conserved sorting-associated protein is mutant in chorea-acanthocytosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.