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Pharmacogenetic Evaluation of Metformin and Sulphonylurea Response in Mexican Mestizos with Type 2 Diabetes.

Current drug metabolism - 1 Jan 2020

Marta Menjivar, Sánchez-Pozos Katy, Jaimes-Santoyo Joel, Monroy-Escutia Jazmin, Rivera-Santiago Carolina, de Los Ángeles Granados-Silvestre María, Ortiz-López María Guadalupe

Abstract excerpt

BACKGROUND: In Mexico, approximately 25% of patients with type 2 diabetes (T2D) have adequate glycemic control. Polymorphisms in pharmacogenetic genes have been shown to have clinical consequences resulting in drug toxicity or therapeutic inefficacy. OBJECTIVE: The study aimed to evaluate the impact of variants in genes known to be involved in response to oral hypoglycemic drugs, such as CYP2C9, OCT, MATE, ABCA1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32407269
DOI: 10.2174/1389200221666200514125443

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