Relative and QuantitativePhosphoproteome Analysisof Macrophages in Response to Infection by Virulent and Avirulent <i>Mycobacteria</i> Reveals a Distinct Role of the Cytosolic RNASensor RIG‑I in <i>Mycobacterium tuberculosis</i> Pathogenesis

Abstract excerpt

Abstract Comparative phosphoproteomics of Mycobacterium tuberculosis (Mtb)- and Mycobacterium bovis BCG (BCG)-infected macrophages could be instrumental in understanding the characteristic post-translational modifications of host proteins and their subsequent involvement in determining Mtb pathogenesis. To identify proteins acquiring a distinct phosphorylation status, herein, we compared the phosphorylation...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Immune cells in cancer
• Share to interferon and immune responses