Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Higher methylation subtype of malignant melanoma and its correlation with thicker progression and worse prognosis.

Cancer medicine - 1 Oct 2020

Yamamoto Yosuke, Matsusaka Keisuke, Fukuyo Masaki, Rahmutulla Bahityar, Matsue Hiroyuki, Kaneda Atsushi

Abstract excerpt

Malignant melanoma (MM) is the most life-threatening disease among all skin malignancies, and recent genome-wide studies reported BRAF, RAS, and NF1 as the most frequently mutated driver genes. While epigenetic aberrations are known to contribute to the oncogenic activity seen in various cancers, their role in MM has not been fully investigated. To investigate the role of epigenetic aberrations in MM, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenesis, Genetic
Share to Epigenomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycoproteins

Share to GTP Phosphohydrolases

Share to Melanoma

Share to Neoplasm Invasiveness

Share to Proto-Oncogene Proteins B-raf

Share to Skin Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 32406600
DOI: 10.1002/cam4.3127
PMCID: PMC7541157

Genes

TFPI2
BRAF
NF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Higher methylation subtype of malignant melanoma and its correlation with thicker progression and worse prognosis.PMID 32406600Read ↗

DNA methylation aberrancy is a reliable prognostic tool in uveal melanomaSemantic proximity Read ↗

DNA methylation profiles in primary cutaneous melanomas are associated with clinically significant pathologic features.Semantic proximity Read ↗

DNA methylation characteristics of primary melanomas with distinct biological behaviour.Semantic proximity Read ↗

Characterization of the CpG Island Hypermethylated Phenotype Subclass in Primary Melanomas.Semantic proximity Read ↗

Comparative Epigenetic Profiling Reveals Distinct Features of Mucosal Melanomas Associated with Immune Cell Infiltration and Their Clinical ImplicationsSemantic proximity Read ↗

CTLA4 methylation predicts response to anti–PD-1 and anti–CTLA-4 immunotherapy in melanoma patientsSemantic proximity Read ↗

CpG island methylator phenotype predicts progression of malignant melanoma.Semantic proximity Read ↗

Whole genome methylation profiles as independent markers of survival in stage IIIC melanoma patientsSemantic proximity Read ↗

DNA Methylation Levels of Melanoma Risk Genes Are Associated with Clinical Characteristics of Melanoma Patients.Semantic proximity Read ↗

Aberrant DNA methylation is associated with aggressive clinicopathological features and poor survival in cutaneous melanoma.Semantic proximity Read ↗

Germline PDCDL1 Gene Variants Are Associated with Increased Primary Melanoma Thickness.Semantic proximity Read ↗

Methylation of PTEN as a Prognostic Factor in Malignant Melanoma of the SkinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.